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Malignant Histiocytosis In the Bernese Mountain Dog

The laboratory of Dr. Elaine Ostrander of the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH) is conducting a study of Malignant Histiocytosis (MH) in Bernese Mountain Dogs. The goal of her team is to first find DNA variation that is associated with the disease and then eventually find the actual mutation that causes the disease. Recent advances with the canine genome project have facilitated the mapping of canine diseases and we are hopeful that we will soon understand the genetic cause of MH in the Bernese Mountain Dog.

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